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saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription

Small activating RNAs (saRNAs) targeting specific promoter regions are able to stimulate gene expression at the transcriptional level, a phenomenon known as RNA activation (RNAa). It is known that RNAa depends on Ago2 and is associated with epigenetic changes at the target promoters. However, the pr...

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Detalles Bibliográficos
Autores principales: Portnoy, Victoria, Lin, Szu Hua Sharon, Li, Kathy H, Burlingame, Alma, Hu, Zheng-Hui, Li, Hao, Li, Long-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783471/
https://www.ncbi.nlm.nih.gov/pubmed/26902284
http://dx.doi.org/10.1038/cr.2016.22

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