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Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample

This data article provides the data generated from additional analyses of a genetic association study, where 7 single nucleotide polymorphisms (SNPs) near/within the brain-derived neurotrophic factor (BDNF) gene were investigated for an association with completed suicide in Slavic population (Ropret...

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Autores principales: Ropret, Sandra, Zupanc, Tomaž, Komel, Radovan, Videtič Paska, Alja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783519/
https://www.ncbi.nlm.nih.gov/pubmed/26966717
http://dx.doi.org/10.1016/j.dib.2015.07.015
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author Ropret, Sandra
Zupanc, Tomaž
Komel, Radovan
Videtič Paska, Alja
author_facet Ropret, Sandra
Zupanc, Tomaž
Komel, Radovan
Videtič Paska, Alja
author_sort Ropret, Sandra
collection PubMed
description This data article provides the data generated from additional analyses of a genetic association study, where 7 single nucleotide polymorphisms (SNPs) near/within the brain-derived neurotrophic factor (BDNF) gene were investigated for an association with completed suicide in Slavic population (Ropret et al., 2015) [1]. One SNP was excluded from the present analyses due to insufficient genotyping rate (rs1491850) and the remaining 6 SNPs (rs7124442, rs10767664, rs962369, rs12273363, rs908867, rs1491851) were analyzed to gain deeper insight into the possible role of these SNPs in the studied phenotype. We present data on logistic regression analyses of: (a) genotypes under four inheritance models, and (b) haplotypes using 2-, 3- and 4-adjacent SNPs sliding window procedure. In both analyses adjustments for potential confounders (age, gender and alcohol dependence syndrome status) were executed. Data may serve as a reference for comparison of the populations with either low or very high suicide rates. The raw genotyping data that could be used in case meta-analyses should be performed may be provided upon request.
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spelling pubmed-47835192016-03-10 Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample Ropret, Sandra Zupanc, Tomaž Komel, Radovan Videtič Paska, Alja Data Brief Data Article This data article provides the data generated from additional analyses of a genetic association study, where 7 single nucleotide polymorphisms (SNPs) near/within the brain-derived neurotrophic factor (BDNF) gene were investigated for an association with completed suicide in Slavic population (Ropret et al., 2015) [1]. One SNP was excluded from the present analyses due to insufficient genotyping rate (rs1491850) and the remaining 6 SNPs (rs7124442, rs10767664, rs962369, rs12273363, rs908867, rs1491851) were analyzed to gain deeper insight into the possible role of these SNPs in the studied phenotype. We present data on logistic regression analyses of: (a) genotypes under four inheritance models, and (b) haplotypes using 2-, 3- and 4-adjacent SNPs sliding window procedure. In both analyses adjustments for potential confounders (age, gender and alcohol dependence syndrome status) were executed. Data may serve as a reference for comparison of the populations with either low or very high suicide rates. The raw genotyping data that could be used in case meta-analyses should be performed may be provided upon request. Elsevier 2015-07-22 /pmc/articles/PMC4783519/ /pubmed/26966717 http://dx.doi.org/10.1016/j.dib.2015.07.015 Text en © 2015 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Ropret, Sandra
Zupanc, Tomaž
Komel, Radovan
Videtič Paska, Alja
Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample
title Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample
title_full Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample
title_fullStr Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample
title_full_unstemmed Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample
title_short Data in support of association study of the brain-derived neurotrophic factor gene SNPs and completed suicide in the Slovenian sample
title_sort data in support of association study of the brain-derived neurotrophic factor gene snps and completed suicide in the slovenian sample
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783519/
https://www.ncbi.nlm.nih.gov/pubmed/26966717
http://dx.doi.org/10.1016/j.dib.2015.07.015
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