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Anticonvulsant and Toxicological Evaluation of Parafluorinated/Chlorinated Derivatives of 3-Hydroxy-3-ethyl-3-phenylpropionamide

Although the anticonvulsant activity of 3-hydroxy-3-ethyl-3-phenylproionamide (HEPP) is well-known, its use is limited by the pharmacotoxicological profile. We herein tested its fluorinated and chlorinated derivatives (F-HEPP and Cl-HEPP) with two seizure models, maximal electroshock seizures (MES),...

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Detalles Bibliográficos
Autores principales:	Garrido-Acosta, Osvaldo, Meza-Toledo, Sergio E., Anguiano-Robledo, Liliana, Soriano-Ursúa, Marvin A., Correa-Basurto, José, Davood, Asghar, Chamorro-Cevallos, Germán
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783531/ https://www.ncbi.nlm.nih.gov/pubmed/27006945 http://dx.doi.org/10.1155/2016/3978010

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