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TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages
Pathogenic bacteria have evolved multiple mechanisms to capture iron or iron-containing heme from host tissues or blood. In response, organisms have developed defense mechanisms to keep iron from pathogens. Very little of the body's iron store is available as free heme; rather nearly all body i...
Autores principales: | Philip, Mary, Chiu, Edison Y., Hajjar, Adeline M., Abkowitz, Janis L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783552/ https://www.ncbi.nlm.nih.gov/pubmed/27006955 http://dx.doi.org/10.1155/2016/4039038 |
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