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A Targeted DNAzyme-Nanocomposite Probe Equipped with Built-in Zn(2+) Arsenal for Combined Treatment of Gene Regulation and Drug Delivery
As catalytic nucleic acids, DNAzymes have been extensively used in the design of sensing platforms. However, their potentials as intelligent drug carriers for responsive drug release in gene therapy and chemotherapy were rarely explored. Herein, we report a dual-functional probe composed of gold nan...
Autores principales: | He, Zhi-Mei, Zhang, Peng-Hui, Li, Xin, Zhang, Jian-Rong, Zhu, Jun-Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783697/ https://www.ncbi.nlm.nih.gov/pubmed/26956167 http://dx.doi.org/10.1038/srep22737 |
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