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A Targeted DNAzyme-Nanocomposite Probe Equipped with Built-in Zn(2+) Arsenal for Combined Treatment of Gene Regulation and Drug Delivery

As catalytic nucleic acids, DNAzymes have been extensively used in the design of sensing platforms. However, their potentials as intelligent drug carriers for responsive drug release in gene therapy and chemotherapy were rarely explored. Herein, we report a dual-functional probe composed of gold nan...

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Detalles Bibliográficos
Autores principales: He, Zhi-Mei, Zhang, Peng-Hui, Li, Xin, Zhang, Jian-Rong, Zhu, Jun-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783697/
https://www.ncbi.nlm.nih.gov/pubmed/26956167
http://dx.doi.org/10.1038/srep22737

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