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Selective advantage of trisomic human cells cultured in non-standard conditions

An abnormal chromosome number, a condition known as aneuploidy, is a ubiquitous feature of cancer cells. A number of studies have shown that aneuploidy impairs cellular fitness. However, there is also evidence that aneuploidy can arise in response to specific challenges and can confer a selective ad...

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Detalles Bibliográficos
Autores principales: Rutledge, Samuel D., Douglas, Temple A., Nicholson, Joshua M., Vila-Casadesús, Maria, Kantzler, Courtney L., Wangsa, Darawalee, Barroso-Vilares, Monika, Kale, Shiv D., Logarinho, Elsa, Cimini, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783771/
https://www.ncbi.nlm.nih.gov/pubmed/26956415
http://dx.doi.org/10.1038/srep22828