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Selective advantage of trisomic human cells cultured in non-standard conditions
An abnormal chromosome number, a condition known as aneuploidy, is a ubiquitous feature of cancer cells. A number of studies have shown that aneuploidy impairs cellular fitness. However, there is also evidence that aneuploidy can arise in response to specific challenges and can confer a selective ad...
Autores principales: | Rutledge, Samuel D., Douglas, Temple A., Nicholson, Joshua M., Vila-Casadesús, Maria, Kantzler, Courtney L., Wangsa, Darawalee, Barroso-Vilares, Monika, Kale, Shiv D., Logarinho, Elsa, Cimini, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783771/ https://www.ncbi.nlm.nih.gov/pubmed/26956415 http://dx.doi.org/10.1038/srep22828 |
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