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The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks

DNA double-strand break (DSB) repair by homologous recombination (HR) involves resection of the break to expose a 3′ single-stranded DNA tail. In budding yeast, resection occurs in two steps: initial short-range resection, performed by Mre11-Rad50-Xrs2 and Sae2; and long-range resection catalysed by...

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Detalles Bibliográficos
Autores principales: Osman, Fekret, Ahn, Jong Sook, Lorenz, Alexander, Whitby, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783781/
https://www.ncbi.nlm.nih.gov/pubmed/26957021
http://dx.doi.org/10.1038/srep22837

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