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Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization

[Image: see text] The purpose of this work is to provide a mechanistic understanding of the dissolution behavior of cocrystals under the influence of ionization and micellar solubilization. Mass transport models were developed by applying Fick’s law of diffusion to dissolution with simultaneous chem...

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Detalles Bibliográficos
Autores principales:	Cao, Fengjuan, Amidon, Gordon L., Rodriguez-Hornedo, Nair, Amidon, Gregory E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783787/ https://www.ncbi.nlm.nih.gov/pubmed/26877267 http://dx.doi.org/10.1021/acs.molpharmaceut.5b00862

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