Cargando…
C-reactive protein levels and body mass index: Elucidating direction of causation through reciprocal Mendelian randomization
CONTEXT: The assignment of direction and causality within networks of observational associations is problematic outside randomized control trials and the presence of causal a relationship between body mass index (BMI) and C-reactive protein (CRP) is disputed. OBJECTIVE: Using reciprocal Mendelian ra...
Autores principales: | Timpson, Nicholas J., Nordestgaard, Børge G., Harbord, Roger M., Zacho, Jeppe, Frayling, Tim M., Tybjærg-Hansen, Anne, Smith, George Davey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783860/ https://www.ncbi.nlm.nih.gov/pubmed/20714329 http://dx.doi.org/10.1038/ijo.2010.137 |
Ejemplares similares
-
The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach
por: Nordestgaard, Børge G., et al.
Publicado: (2012) -
Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
por: Palmer, Tom M, et al.
Publicado: (2013) -
Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study
por: Carter, Alice R., et al.
Publicado: (2019) -
The methylenetetrahydrofolate reductase C677T genotype and the risk of obesity in three large population-based cohorts
por: Lewis, Sarah J, et al.
Publicado: (2008) -
Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer’s disease and Parkinson’s disease: Mendelian randomisation study
por: Benn, Marianne, et al.
Publicado: (2017)