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Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified...
Autores principales: | Abdullah, Nor Hayati, Thomas, Noel Francis, Sivasothy, Yasodha, Lee, Vannajan Sanghiran, Liew, Sook Yee, Noorbatcha, Ibrahim Ali, Awang, Khalijah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783877/ https://www.ncbi.nlm.nih.gov/pubmed/26907251 http://dx.doi.org/10.3390/ijms17020143 |
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