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Subchronic Exposure to Arsenic Represses the TH/TRβ1-CaMK IV Signaling Pathway in Mouse Cerebellum

We previously reported that arsenic (As) impaired learning and memory by down-regulating calmodulin-dependent protein kinase IV (CaMK IV) in mouse cerebellum. It has been documented that the thyroid hormone receptor (TR)/retinoid X receptor (RXR) heterodimer and thyroid hormone (TH) may be involved...

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Detalles Bibliográficos
Autores principales: Guan, Huai, Li, Shuangyue, Guo, Yanjie, Liu, Xiaofeng, Yang, Yi, Guo, Jinqiu, Li, Sheng, Zhang, Cong, Shang, Lixin, Piao, Fengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783891/
https://www.ncbi.nlm.nih.gov/pubmed/26821021
http://dx.doi.org/10.3390/ijms17020157