Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish

Orchestrated protein synthesis and degradation is fundamental for proper cell function. In muscle, impairment of proteostasis often leads to severe cellular defects finally interfering with contractile function. Here, we analyze for the first time the role of Atrogin-1, a muscle-specific E3 ubiquiti...

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Detalles Bibliográficos
Autores principales: Bühler, Anja, Kustermann, Monika, Bummer, Tiziana, Rottbauer, Wolfgang, Sandri, Marco, Just, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783921/
https://www.ncbi.nlm.nih.gov/pubmed/26840306
http://dx.doi.org/10.3390/ijms17020187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783921/
https://www.ncbi.nlm.nih.gov/pubmed/26840306
http://dx.doi.org/10.3390/ijms17020187

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