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Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients

Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza...

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Autores principales: Reddy, Krishna P., Bajwa, Ednan K., Parker, Robert A., Onderdonk, Andrew B., Walensky, Rochelle P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784015/
https://www.ncbi.nlm.nih.gov/pubmed/26966696
http://dx.doi.org/10.1093/ofid/ofw023
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author Reddy, Krishna P.
Bajwa, Ednan K.
Parker, Robert A.
Onderdonk, Andrew B.
Walensky, Rochelle P.
author_facet Reddy, Krishna P.
Bajwa, Ednan K.
Parker, Robert A.
Onderdonk, Andrew B.
Walensky, Rochelle P.
author_sort Reddy, Krishna P.
collection PubMed
description Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis.
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spelling pubmed-47840152016-03-10 Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients Reddy, Krishna P. Bajwa, Ednan K. Parker, Robert A. Onderdonk, Andrew B. Walensky, Rochelle P. Open Forum Infect Dis Brief Reports Among critically ill patients with lower respiratory tract (LRT)-confirmed influenza, we retrospectively observed worse 28-day clinical outcomes in upper respiratory tract (URT)-negative versus URT-positive subjects. This finding may reflect disease progression and highlights the need for influenza testing of both URT and LRT specimens to improve diagnostic yield and possibly inform prognosis. Oxford University Press 2016-03-08 /pmc/articles/PMC4784015/ /pubmed/26966696 http://dx.doi.org/10.1093/ofid/ofw023 Text en © The Author 2016. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Reddy, Krishna P.
Bajwa, Ednan K.
Parker, Robert A.
Onderdonk, Andrew B.
Walensky, Rochelle P.
Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
title Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
title_full Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
title_fullStr Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
title_full_unstemmed Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
title_short Relationship Between Upper Respiratory Tract Influenza Test Result and Clinical Outcomes Among Critically Ill Influenza Patients
title_sort relationship between upper respiratory tract influenza test result and clinical outcomes among critically ill influenza patients
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784015/
https://www.ncbi.nlm.nih.gov/pubmed/26966696
http://dx.doi.org/10.1093/ofid/ofw023
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