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Dynamic reorganization of the actin cytoskeleton
Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structure...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784019/ https://www.ncbi.nlm.nih.gov/pubmed/26989473 http://dx.doi.org/10.12688/f1000research.6374.1 |
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author | Letort, Gaëlle Ennomani, Hajer Gressin, Laurène Théry, Manuel Blanchoin, Laurent |
author_facet | Letort, Gaëlle Ennomani, Hajer Gressin, Laurène Théry, Manuel Blanchoin, Laurent |
author_sort | Letort, Gaëlle |
collection | PubMed |
description | Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of another. Here, we discuss such transitions and illustrate them with computer simulations. |
format | Online Article Text |
id | pubmed-4784019 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-47840192016-03-16 Dynamic reorganization of the actin cytoskeleton Letort, Gaëlle Ennomani, Hajer Gressin, Laurène Théry, Manuel Blanchoin, Laurent F1000Res Review Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of another. Here, we discuss such transitions and illustrate them with computer simulations. F1000Research 2015-10-01 /pmc/articles/PMC4784019/ /pubmed/26989473 http://dx.doi.org/10.12688/f1000research.6374.1 Text en Copyright: © 2015 Letort G et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Letort, Gaëlle Ennomani, Hajer Gressin, Laurène Théry, Manuel Blanchoin, Laurent Dynamic reorganization of the actin cytoskeleton |
title | Dynamic reorganization of the actin cytoskeleton |
title_full | Dynamic reorganization of the actin cytoskeleton |
title_fullStr | Dynamic reorganization of the actin cytoskeleton |
title_full_unstemmed | Dynamic reorganization of the actin cytoskeleton |
title_short | Dynamic reorganization of the actin cytoskeleton |
title_sort | dynamic reorganization of the actin cytoskeleton |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784019/ https://www.ncbi.nlm.nih.gov/pubmed/26989473 http://dx.doi.org/10.12688/f1000research.6374.1 |
work_keys_str_mv | AT letortgaelle dynamicreorganizationoftheactincytoskeleton AT ennomanihajer dynamicreorganizationoftheactincytoskeleton AT gressinlaurene dynamicreorganizationoftheactincytoskeleton AT therymanuel dynamicreorganizationoftheactincytoskeleton AT blanchoinlaurent dynamicreorganizationoftheactincytoskeleton |