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Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation)
INTRODUCTION: Laghu Malini Vasanta (LMV) Rasa is a well-known Vasanta Kalpa (formulation). As per reference of Yoga Ratnakara, Rasaka and Maricha are chief ingredients in 2:1 proportion. Bhavana (levigation) is said to be given first with Navaneeta (freshly prepared cow's butter) and then with...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784130/ https://www.ncbi.nlm.nih.gov/pubmed/27011721 http://dx.doi.org/10.4103/0974-8520.175535 |
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author | Walunj, Manisha B. Patgiri, Biswajyoti Shukla, Vinay J. Prajapati, Pradeep Kumar |
author_facet | Walunj, Manisha B. Patgiri, Biswajyoti Shukla, Vinay J. Prajapati, Pradeep Kumar |
author_sort | Walunj, Manisha B. |
collection | PubMed |
description | INTRODUCTION: Laghu Malini Vasanta (LMV) Rasa is a well-known Vasanta Kalpa (formulation). As per reference of Yoga Ratnakara, Rasaka and Maricha are chief ingredients in 2:1 proportion. Bhavana (levigation) is said to be given first with Navaneeta (freshly prepared cow's butter) and then with Nimbu Swarasa (lemon juice) until Ghrita Vimukta stage is reached. Quantity of Bhavana Dravya (levigating media) and duration of levigation are not mentioned. AIMS: To develop standard manufacturing procedure of LMV Rasa. MATERIALS AND METHODS: The study was carried out in two stages - preparation of Yashada Bhasma and preparation of LMV Rasa and its tablet. A pilot study was carried out to fix quantity of cow's butter as levigation media. Based on results of the pilot study, LMV Rasa was prepared in two groups, that is, LMV 50 (LMV Rasa - prepared with weight of freshly prepared butter in 50% quantity of total ingredients) and LMV 75 (LMV Rasa prepared with weight of freshly prepared butter in 75% quantity of total ingredients). Complete drying of levigated mass and minimal spreading of fatty portion on filter paper was considered as the end point of levigation. Tablets of both samples were prepared by adding Pippali and honey in it and analyzed for their quality control parameters. RESULTS: Twenty-eight hours duration of repeated levigation was required in LMV 50 which was prolonged up to 48 h in batch carried out in rainy season. In LMV 75, comparatively maximum duration of 54 h was required for levigation which was prolonged in the rainy season to 88 h. In both groups, lemon juice required for repeated levigation was 10 times of quantity of butter added initially. CONCLUSION: From pharmaceutical point of view, preparation of LMV Rasa tablets with quantity of butter in 50% of total ingredients is more convenient. |
format | Online Article Text |
id | pubmed-4784130 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-47841302016-03-23 Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) Walunj, Manisha B. Patgiri, Biswajyoti Shukla, Vinay J. Prajapati, Pradeep Kumar Ayu Pharmaceutical Standardization INTRODUCTION: Laghu Malini Vasanta (LMV) Rasa is a well-known Vasanta Kalpa (formulation). As per reference of Yoga Ratnakara, Rasaka and Maricha are chief ingredients in 2:1 proportion. Bhavana (levigation) is said to be given first with Navaneeta (freshly prepared cow's butter) and then with Nimbu Swarasa (lemon juice) until Ghrita Vimukta stage is reached. Quantity of Bhavana Dravya (levigating media) and duration of levigation are not mentioned. AIMS: To develop standard manufacturing procedure of LMV Rasa. MATERIALS AND METHODS: The study was carried out in two stages - preparation of Yashada Bhasma and preparation of LMV Rasa and its tablet. A pilot study was carried out to fix quantity of cow's butter as levigation media. Based on results of the pilot study, LMV Rasa was prepared in two groups, that is, LMV 50 (LMV Rasa - prepared with weight of freshly prepared butter in 50% quantity of total ingredients) and LMV 75 (LMV Rasa prepared with weight of freshly prepared butter in 75% quantity of total ingredients). Complete drying of levigated mass and minimal spreading of fatty portion on filter paper was considered as the end point of levigation. Tablets of both samples were prepared by adding Pippali and honey in it and analyzed for their quality control parameters. RESULTS: Twenty-eight hours duration of repeated levigation was required in LMV 50 which was prolonged up to 48 h in batch carried out in rainy season. In LMV 75, comparatively maximum duration of 54 h was required for levigation which was prolonged in the rainy season to 88 h. In both groups, lemon juice required for repeated levigation was 10 times of quantity of butter added initially. CONCLUSION: From pharmaceutical point of view, preparation of LMV Rasa tablets with quantity of butter in 50% of total ingredients is more convenient. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4784130/ /pubmed/27011721 http://dx.doi.org/10.4103/0974-8520.175535 Text en Copyright: © 2015 AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Pharmaceutical Standardization Walunj, Manisha B. Patgiri, Biswajyoti Shukla, Vinay J. Prajapati, Pradeep Kumar Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) |
title | Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) |
title_full | Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) |
title_fullStr | Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) |
title_full_unstemmed | Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) |
title_short | Standard manufacturing procedure for Laghu Malini Vasanta Rasa in context of Bhavana (levigation) |
title_sort | standard manufacturing procedure for laghu malini vasanta rasa in context of bhavana (levigation) |
topic | Pharmaceutical Standardization |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784130/ https://www.ncbi.nlm.nih.gov/pubmed/27011721 http://dx.doi.org/10.4103/0974-8520.175535 |
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