Ultra-precise detection of mutations by droplet-based amplification of circularized DNA

BACKGROUND: NGS (next generation sequencing) has been widely used in studies of biological processes, ranging from microbial evolution to cancer genomics. However, the error rate of NGS (0.1 % ~ 1 %) is still remaining a great challenge for comprehensively investigating the low frequency variations,...

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Detalles Bibliográficos
Autores principales: Wang, Kaile, Ma, Qin, Jiang, Lan, Lai, Shujuan, Lu, Xuemei, Hou, Yali, Wu, Chung-I, Ruan, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784281/
https://www.ncbi.nlm.nih.gov/pubmed/26960407
http://dx.doi.org/10.1186/s12864-016-2480-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784281/
https://www.ncbi.nlm.nih.gov/pubmed/26960407
http://dx.doi.org/10.1186/s12864-016-2480-1

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