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Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models

BACKGROUND: Sorafenib is recognized as a standard treatment for advanced hepatocellular carcinoma (HCC). However, many patients have to adopt dose reduction or terminate the use of sorafenib because of side effects. In addition, a large number of patients are resistant to sorafenib. Thus, it is esse...

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Detalles Bibliográficos
Autores principales:	You, Abin, Cao, Manqing, Guo, Zhigui, Zuo, Bingfeng, Gao, Junrong, Zhou, Hongyuan, Li, Huikai, Cui, Yunlong, Fang, Feng, Zhang, Wei, Song, Tianqiang, Li, Qiang, Zhu, Xiaolin, Yin, Haifang, Sun, Huichuan, Zhang, Ti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784359/ https://www.ncbi.nlm.nih.gov/pubmed/26957312 http://dx.doi.org/10.1186/s13045-016-0253-6

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