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Transcription factor CCAAT/enhancer binding protein alpha up-regulates microRNA let-7a-1 in lung cancer cells by direct binding

AIMS: The transcription factor CCAAT/enhancer binding protein α (C/EBPα) and microRNA (miRNA) let-7a-1 act as tumor suppressors in many types of cancers including lung cancer. In the present study, we aim to investigate whether let-7a-1 is a novel important target of C/EBPα in lung cancer cells. MET...

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Detalles Bibliográficos
Autores principales: Lin, Yani, Zhao, Jian, Hu, Xiaoyan, Wang, Lina, Liang, Liming, Chen, Weiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784402/
https://www.ncbi.nlm.nih.gov/pubmed/26962302
http://dx.doi.org/10.1186/s12935-016-0294-5