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Tackling the crystallographic structure determination of the COP9 signalosome

The COP9 signalosome (CSN) is an essential multi-protein complex in eukaryotes. CSN is a master regulator of intracellular protein degradation, controlling the vast family of cullin–RING ubiquitin (E3) ligases (CRLs). Important in many cellular processes, CSN has prominent roles in DNA repair, cell-...

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Detalles Bibliográficos
Autor principal:	Bunker, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2016
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784664/ https://www.ncbi.nlm.nih.gov/pubmed/26960120 http://dx.doi.org/10.1107/S2059798316001169

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