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Initiating heavy-atom-based phasing by multi-dimensional molecular replacement

To obtain an electron-density map from a macromolecular crystal the phase problem needs to be solved, which often involves the use of heavy-atom derivative crystals and concomitant heavy-atom substructure determination. This is typically performed by dual-space methods, direct methods or Patterson-b...

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Detalles Bibliográficos
Autores principales: Pedersen, Bjørn Panyella, Gourdon, Pontus, Liu, Xiangyu, Karlsen, Jesper Lykkegaard, Nissen, Poul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784675/
https://www.ncbi.nlm.nih.gov/pubmed/26960131
http://dx.doi.org/10.1107/S2059798315022482