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Developmental Foreign Accent Syndrome: Report of a New Case

This paper presents the case of a 17-year-old right-handed Belgian boy with developmental FAS and comorbid developmental apraxia of speech (DAS). Extensive neuropsychological and neurolinguistic investigations demonstrated a normal IQ but impaired planning (visuo-constructional dyspraxia). A Tc-99m-...

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Autores principales: Keulen, Stefanie, Mariën, Peter, Wackenier, Peggy, Jonkers, Roel, Bastiaanse, Roelien, Verhoeven, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785140/
https://www.ncbi.nlm.nih.gov/pubmed/27014011
http://dx.doi.org/10.3389/fnhum.2016.00065
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author Keulen, Stefanie
Mariën, Peter
Wackenier, Peggy
Jonkers, Roel
Bastiaanse, Roelien
Verhoeven, Jo
author_facet Keulen, Stefanie
Mariën, Peter
Wackenier, Peggy
Jonkers, Roel
Bastiaanse, Roelien
Verhoeven, Jo
author_sort Keulen, Stefanie
collection PubMed
description This paper presents the case of a 17-year-old right-handed Belgian boy with developmental FAS and comorbid developmental apraxia of speech (DAS). Extensive neuropsychological and neurolinguistic investigations demonstrated a normal IQ but impaired planning (visuo-constructional dyspraxia). A Tc-99m-ECD SPECT revealed a significant hypoperfusion in the prefrontal and medial frontal regions, as well as in the lateral temporal regions. Hypoperfusion in the right cerebellum almost reached significance. It is hypothesized that these clinical findings support the view that FAS and DAS are related phenomena following impairment of the cerebro-cerebellar network.
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spelling pubmed-47851402016-03-24 Developmental Foreign Accent Syndrome: Report of a New Case Keulen, Stefanie Mariën, Peter Wackenier, Peggy Jonkers, Roel Bastiaanse, Roelien Verhoeven, Jo Front Hum Neurosci Neuroscience This paper presents the case of a 17-year-old right-handed Belgian boy with developmental FAS and comorbid developmental apraxia of speech (DAS). Extensive neuropsychological and neurolinguistic investigations demonstrated a normal IQ but impaired planning (visuo-constructional dyspraxia). A Tc-99m-ECD SPECT revealed a significant hypoperfusion in the prefrontal and medial frontal regions, as well as in the lateral temporal regions. Hypoperfusion in the right cerebellum almost reached significance. It is hypothesized that these clinical findings support the view that FAS and DAS are related phenomena following impairment of the cerebro-cerebellar network. Frontiers Media S.A. 2016-03-10 /pmc/articles/PMC4785140/ /pubmed/27014011 http://dx.doi.org/10.3389/fnhum.2016.00065 Text en Copyright © 2016 Keulen, Mariën, Wackenier, Jonkers, Bastiaanse and Verhoeven. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Keulen, Stefanie
Mariën, Peter
Wackenier, Peggy
Jonkers, Roel
Bastiaanse, Roelien
Verhoeven, Jo
Developmental Foreign Accent Syndrome: Report of a New Case
title Developmental Foreign Accent Syndrome: Report of a New Case
title_full Developmental Foreign Accent Syndrome: Report of a New Case
title_fullStr Developmental Foreign Accent Syndrome: Report of a New Case
title_full_unstemmed Developmental Foreign Accent Syndrome: Report of a New Case
title_short Developmental Foreign Accent Syndrome: Report of a New Case
title_sort developmental foreign accent syndrome: report of a new case
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785140/
https://www.ncbi.nlm.nih.gov/pubmed/27014011
http://dx.doi.org/10.3389/fnhum.2016.00065
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