Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice

Late-onset hypogonadism (i.e. androgen deficiency) raises the risk for abdominal obesity in men. The mechanism for this obesity is unclear. Here, we demonstrated that hypogonadism after castration caused abdominal obesity in high-fat diet (HFD)-fed, but not in standard diet (SD)-fed, C57BL/6J mice....

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Detalles Bibliográficos
Autores principales: Harada, Naoki, Hanaoka, Ryo, Horiuchi, Hiroko, Kitakaze, Tomoya, Mitani, Takakazu, Inui, Hiroshi, Yamaji, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785334/
https://www.ncbi.nlm.nih.gov/pubmed/26961573
http://dx.doi.org/10.1038/srep23001

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