Cargando…

Carnosic acid slows photoreceptor degeneration in the Pde6b(rd10) mouse model of retinitis pigmentosa

The photoreceptor cell death associated with the various genetic forms of retinitis pigmentosa (RP) is currently untreatable and leads to partial or complete vision loss. Carnosic acid (CA) upregulates endogenous antioxidant enzymes and has proven neuroprotective in studies of neurodegenerative mode...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Kai, Tarchick, Matthew J., Yu, Xiaoshan, Beight, Craig, Bu, Ping, Yu, Minzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785376/ https://www.ncbi.nlm.nih.gov/pubmed/26961159 http://dx.doi.org/10.1038/srep22632

Ejemplares similares

Lutein and Zeaxanthin Isomers Reduce Photoreceptor Degeneration in the Pde6b(rd10) Mouse Model of Retinitis Pigmentosa
por: Yu, Minzhong, et al.
Publicado: (2018)

Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa
por: Tomita, Yohei, et al.
Publicado: (2021)

Lutein delays photoreceptor degeneration in a mouse model of retinitis pigmentosa
por: Zhang, Hui-Jun, et al.
Publicado: (2021)

Electrophysiological and Histologic Evaluation of the Time Course of Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa
por: Jae, Seol A, et al.
Publicado: (2013)

Thioredoxin Delays Photoreceptor Degeneration, Oxidative and Inflammation Alterations in Retinitis Pigmentosa
por: Gimeno-Hernández, Roberto, et al.
Publicado: (2020)

Luteolin delays photoreceptor degeneration in a mouse model of retinitis pigmentosa
por: Liu, Xiao-Bin, et al.
Publicado: (2021)

Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice
por: Mitton, Kenneth P., et al.
Publicado: (2014)

Mechanisms of Photoreceptor Death in Retinitis Pigmentosa
por: Newton, Fay, et al.
Publicado: (2020)

Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa
por: Rex, Tonia S., et al.
Publicado: (2016)

A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors
por: Santhanam, Abirami, et al.
Publicado: (2020)

Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa
por: Mercau, Maria E., et al.
Publicado: (2023)

A Ketogenic & Low-Protein Diet Slows Retinal Degeneration in rd10 Mice
por: Ryals, Renee C., et al.
Publicado: (2020)

Restoration of Cone Photoreceptor Function in Retinitis Pigmentosa
por: Kaplan, Henry J., et al.
Publicado: (2017)

Metabolic rescue of cone photoreceptors in retinitis pigmentosa
por: Kaplan, Henry J., et al.
Publicado: (2021)

Clinical Phenotype of PDE6B-Associated Retinitis Pigmentosa
por: Kuehlewein, Laura, et al.
Publicado: (2021)

Lutein and Zeaxanthin Isomers Protect against Light-Induced Retinopathy via Decreasing Oxidative and Endoplasmic Reticulum Stress in BALB/cJ Mice
por: Yu, Minzhong, et al.
Publicado: (2018)

Use of Hydrogen as a Novel Therapeutic Strategy Against Photoreceptor Degeneration in Retinitis Pigmentosa Patients
por: Tao, Ye, et al.
Publicado: (2016)

Temporal Contrast Sensitivity Increases despite Photoreceptor Degeneration in a Mouse Model of Retinitis Pigmentosa
por: Pasquale, Rose L., et al.
Publicado: (2021)

Novel PDE6A mutation in an Emirati patient with retinitis pigmentosa
por: Nair, Pratibha, et al.
Publicado: (2017)

XIAP Protection of Photoreceptors in Animal Models of Retinitis Pigmentosa
por: Leonard, Kevin C., et al.
Publicado: (2007)

Necrotic cone photoreceptor cell death in retinitis pigmentosa
por: Murakami, Y, et al.
Publicado: (2015)

Assessing Photoreceptor Structure in Retinitis Pigmentosa and Usher Syndrome
por: Sun, Lynn W., et al.
Publicado: (2016)

Cone photoreceptor dysfunction in retinitis pigmentosa revealed by optoretinography
por: Lassoued, Ayoub, et al.
Publicado: (2021)

A profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa
por: Uren, Philip J., et al.
Publicado: (2014)

Development and Degeneration of Cone Bipolar Cells Are Independent of Cone Photoreceptors in a Mouse Model of Retinitis Pigmentosa
por: Chen, Miao, et al.
Publicado: (2012)

Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa
por: Vargas, Andrew, et al.
Publicado: (2017)

HDAC inhibition delays photoreceptor loss in Pde6b mutant mice of retinitis pigmentosa: insights from scRNA-seq and CUT&Tag
por: Dong, Yujie, et al.
Publicado: (2023)

The Role of Mislocalized Phototransduction in Photoreceptor Cell Death of Retinitis Pigmentosa
por: Nakao, Takeshi, et al.
Publicado: (2012)

Investigations Into Bioenergetic Neuroprotection of Cone Photoreceptors: Relevance to Retinitis Pigmentosa
por: Narayan, Daniel S., et al.
Publicado: (2019)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
por: Lee, Sang Joon, et al.
Publicado: (2023)

Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa
por: Blank, Thomas, et al.
Publicado: (2018)

Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa
por: Yang, Huan, et al.
Publicado: (2017)

The Effect of Cyanine Dye NK-4 on Photoreceptor Degeneration in a Rat Model of Early-Stage Retinitis Pigmentosa
por: Liu, Shihui, et al.
Publicado: (2021)

Novel Localization of Peripherin 2, the Photoreceptor-Specific Retinal Degeneration Slow Protein, in Retinal Pigment Epithelium
por: Uhl, Patrizia B., et al.
Publicado: (2015)

Spatio-temporal characterization of S- and M/L-cone degeneration in the Rd1 mouse model of retinitis pigmentosa
por: Narayan, Daniel S., et al.
Publicado: (2019)

Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 mice
por: Picard, Emilie, et al.
Publicado: (2010)

Novel variants in PDE6A and PDE6B genes and its phenotypes in patients with retinitis pigmentosa in Chinese families
por: Li, Yuyu, et al.
Publicado: (2022)

Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration
por: Murga-Zamalloa, Carlos A., et al.
Publicado: (2010)

Minocycline decreases CCR2-positive monocytes in the retina and ameliorates photoreceptor degeneration in a mouse model of retinitis pigmentosa
por: Terauchi, Ryo, et al.
Publicado: (2021)

Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa
por: Mowat, Freya M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9cob22fjhrk1di43v5c16lsa5j