Cargando…
Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke
There is an urgent need for a therapy that reverses disability after stroke when initiated in a time frame suitable for the majority of new victims. We show here that intramuscular delivery of neurotrophin-3 (NT3, encoded by NTF3 ) can induce sensorimotor recovery when treatment is initiated 24 h af...
Autores principales: | Duricki, Denise A., Hutson, Thomas H., Kathe, Claudia, Soleman, Sara, Gonzalez-Carter, Daniel, Petruska, Jeffrey C., Shine, H. David, Chen, Qin, Wood, Tobias C., Bernanos, Michel, Cash, Diana, Williams, Steven C. R., Gage, Fred H., Moon, Lawrence D. F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785394/ https://www.ncbi.nlm.nih.gov/pubmed/26614754 http://dx.doi.org/10.1093/brain/awv341 |
Ejemplares similares
-
Stroke Recovery in Rats after 24‐Hour–Delayed Intramuscular Neurotrophin‐3 Infusion
por: Duricki, Denise A., et al.
Publicado: (2018) -
Intramuscular Neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats
por: Kathe, Claudia, et al.
Publicado: (2016) -
RNA sequencing dataset describing transcriptional changes in cervical dorsal root ganglia after bilateral pyramidotomy and forelimb intramuscular gene therapy with an adeno-associated viral vector encoding human neurotrophin-3
por: Kathe, Claudia, et al.
Publicado: (2018) -
Delayed peripheral treatment with neurotrophin-3 improves sensorimotor recovery after central nervous system injury
por: Kakanos, Sotiris G., et al.
Publicado: (2019) -
Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies
por: Kathe, Claudia, et al.
Publicado: (2014)