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CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress
The glutathione/cysteine exporter CydDC maintains redox balance in Escherichia coli. A cydD mutant strain was used to probe the influence of CydDC upon reduced thiol export, gene expression, metabolic perturbations, intracellular pH homoeostasis and tolerance to nitric oxide (NO). Loss of CydDC was...
Autores principales: | Holyoake, Louise V., Hunt, Stuart, Sanguinetti, Guido, Cook, Gregory M., Howard, Mark J., Rowe, Michelle L., Poole, Robert K., Shepherd, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785604/ https://www.ncbi.nlm.nih.gov/pubmed/26699904 http://dx.doi.org/10.1042/BJ20150536 |
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