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Indomethacin treatment prior to pentylenetetrazole-induced seizures downregulates the expression of il1b and cox2 and decreases seizure-like behavior in zebrafish larvae

BACKGROUND: It has been demonstrated that the zebrafish model of pentylenetetrazole (PTZ)-evoked seizures and the well-established rodent models of epilepsy are similar pertaining to behavior, electrographic features, and c-fos expression. Although this zebrafish model is suitable for studying seizu...

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Detalles Bibliográficos
Autores principales:	Barbalho, Patrícia Gonçalves, Lopes-Cendes, Iscia, Maurer-Morelli, Claudia Vianna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785663/ https://www.ncbi.nlm.nih.gov/pubmed/26961169 http://dx.doi.org/10.1186/s12868-016-0246-y

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