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Tuberculosis presenting as posttraumatic panophthalmitis

Panophthalmitis is one of rare manifestations of tuberculosis described in atypical situations such as children, immune compromised patients, or drug abuse. The present report describes the first case of tubercular panophthalmitis developing after trauma in an otherwise healthy adult patient. A 46-y...

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Autores principales: Gupta, Pankaj, Singh, Ramandeep, Gupta, Suruchi, Kumar, Abhiraj, Kakkar, Nandita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785710/
https://www.ncbi.nlm.nih.gov/pubmed/27013830
http://dx.doi.org/10.4103/0974-620X.176102
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author Gupta, Pankaj
Singh, Ramandeep
Gupta, Suruchi
Kumar, Abhiraj
Kakkar, Nandita
author_facet Gupta, Pankaj
Singh, Ramandeep
Gupta, Suruchi
Kumar, Abhiraj
Kakkar, Nandita
author_sort Gupta, Pankaj
collection PubMed
description Panophthalmitis is one of rare manifestations of tuberculosis described in atypical situations such as children, immune compromised patients, or drug abuse. The present report describes the first case of tubercular panophthalmitis developing after trauma in an otherwise healthy adult patient. A 46-year-old female patient presented with corneal infiltrate and endophthalmitis that developed after an injury to right eye with wooden object. Corneal scrapings and vitreous tap were sterile. The patient did not improve with antibiotics and developed panophthalmitis. On evisceration of the painful blind eye, histopathology showed the presence of granulomatous inflammation and acid-fast bacilli. The patient had no other systemic focus of tubercular infection. The patient was managed with anti-tubercular therapy for 6 months. Atypical presentations of tuberculosis like panophthalmitis pose a difficult problem in diagnosis as well as treatment. Direct inoculation of bacilli during trauma is a rare source of infection. This case report presents unusual development of tubercular panophthalmitis following direct inoculation of bacilli during trauma. Ocular tuberculosis should be considered in differential diagnosis of posttraumatic endophthalmitis and panophthalmitis, especially in endemic regions like India.
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spelling pubmed-47857102016-03-24 Tuberculosis presenting as posttraumatic panophthalmitis Gupta, Pankaj Singh, Ramandeep Gupta, Suruchi Kumar, Abhiraj Kakkar, Nandita Oman J Ophthalmol Case Report Panophthalmitis is one of rare manifestations of tuberculosis described in atypical situations such as children, immune compromised patients, or drug abuse. The present report describes the first case of tubercular panophthalmitis developing after trauma in an otherwise healthy adult patient. A 46-year-old female patient presented with corneal infiltrate and endophthalmitis that developed after an injury to right eye with wooden object. Corneal scrapings and vitreous tap were sterile. The patient did not improve with antibiotics and developed panophthalmitis. On evisceration of the painful blind eye, histopathology showed the presence of granulomatous inflammation and acid-fast bacilli. The patient had no other systemic focus of tubercular infection. The patient was managed with anti-tubercular therapy for 6 months. Atypical presentations of tuberculosis like panophthalmitis pose a difficult problem in diagnosis as well as treatment. Direct inoculation of bacilli during trauma is a rare source of infection. This case report presents unusual development of tubercular panophthalmitis following direct inoculation of bacilli during trauma. Ocular tuberculosis should be considered in differential diagnosis of posttraumatic endophthalmitis and panophthalmitis, especially in endemic regions like India. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4785710/ /pubmed/27013830 http://dx.doi.org/10.4103/0974-620X.176102 Text en Copyright: © Oman Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gupta, Pankaj
Singh, Ramandeep
Gupta, Suruchi
Kumar, Abhiraj
Kakkar, Nandita
Tuberculosis presenting as posttraumatic panophthalmitis
title Tuberculosis presenting as posttraumatic panophthalmitis
title_full Tuberculosis presenting as posttraumatic panophthalmitis
title_fullStr Tuberculosis presenting as posttraumatic panophthalmitis
title_full_unstemmed Tuberculosis presenting as posttraumatic panophthalmitis
title_short Tuberculosis presenting as posttraumatic panophthalmitis
title_sort tuberculosis presenting as posttraumatic panophthalmitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785710/
https://www.ncbi.nlm.nih.gov/pubmed/27013830
http://dx.doi.org/10.4103/0974-620X.176102
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