Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy

Severe myoclonic epilepsy of infancy (SMEI) is associated with loss of function of the SCN1A gene encoding the Na(V)1.1 sodium channel isoform. Previous studies in Scn1a(−/+) mice during the pre-epileptic period reported selective reduction in interneuron excitability and proposed this as the main p...

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Detalles Bibliográficos
Autores principales: De Stasi, Angela Michela, Farisello, Pasqualina, Marcon, Iacopo, Cavallari, Stefano, Forli, Angelo, Vecchia, Dania, Losi, Gabriele, Mantegazza, Massimo, Panzeri, Stefano, Carmignoto, Giorgio, Bacci, Alberto, Fellin, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785957/
https://www.ncbi.nlm.nih.gov/pubmed/26819275
http://dx.doi.org/10.1093/cercor/bhw002

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