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Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia

BACKGROUND: Patients with acute myeloid leukemia (AML) who undergo induction chemotherapy are at high risk for invasive fungal disease (IFD). Dectin-1, a C-type lectin family member represents one of the most important pattern recognition receptors of the innate immune system and single nucleotide p...

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Detalles Bibliográficos
Autores principales: Fischer, Mike, Spies-Weisshart, Baerbel, Schrenk, Karin, Gruhn, Bernd, Wittig, Susan, Glaser, Anita, Hochhaus, Andreas, Scholl, Sebastian, Schnetzke, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786091/
https://www.ncbi.nlm.nih.gov/pubmed/26963509
http://dx.doi.org/10.1371/journal.pone.0150632