Cargando…

Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis

The landscape of translational research has been shifting toward drug combination therapies. Pairing of drugs allows for more types of drug interaction with cells. In order to accurately and comprehensively assess combinational drug efficacy, analytical methods capable of recognizing these alternati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sima, Chao, Hua, Jianping, Cypert, Milana, Miller, Tasha, Wilson-Robles, Heather M., Trent, Jeffrey M., Dougherty, Edward R., Bittner, Michael L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786100/ https://www.ncbi.nlm.nih.gov/pubmed/26997864 http://dx.doi.org/10.4137/CIN.S30799

Ejemplares similares

Comprehensive live-cell imaging analysis of cryptotanshinone and synergistic drug-screening effects in various human and canine cancer cell lines
por: Bittner, Michael L., et al.
Publicado: (2021)

Phenotype Classification Using Moment Features of Single-Cell Data
por: Sima, Chao, et al.
Publicado: (2018)

Dynamical modeling of uncertain interaction-based genomic networks
por: Mohsenizadeh, Daniel N, et al.
Publicado: (2015)

Performance of Feature Selection Methods
por: Dougherty, Edward R, et al.
Publicado: (2009)

Assessing the efficacy of molecularly targeted agents on cell line-based platforms by using system identification
por: Li, Xiangfang, et al.
Publicado: (2012)

Evaluating Gene Set Enrichment Analysis Via a Hybrid Data Model
por: Hua, Jianping, et al.
Publicado: (2014)

Analysis of Expression Patterns: The Scope of the Problem, the Problem of Scope
por: Chen, Yidong, et al.
Publicado: (2001)

Creer y lograr
por: Cypert, Samuel A.
Publicado: (1990)

Characterization of five newly derived canine osteosarcoma cell lines
por: Wilson-Robles, Heather, et al.
Publicado: (2019)

Feasibility and safety of whole lung irradiation in the treatment of canine appendicular osteosarcoma
por: Brehm, Amanda, et al.
Publicado: (2021)

An in-silico study examining the induction of apoptosis by Cryptotanshinone in metastatic melanoma cell lines
por: Saraf, Radhika S., et al.
Publicado: (2018)

Targeting oncogenic mutations in colorectal cancer using cryptotanshinone
por: Vundavilli, Haswanth, et al.
Publicado: (2021)

Normalization Benefits Microarray-Based Classification
por: Hua, Jianping, et al.
Publicado: (2006)

Dynamical modeling of drug effect using hybrid systems
por: Li, Xiangfang, et al.
Publicado: (2012)

A Systems Biology Approach in Therapeutic Response Study for Different Dosing Regimens—a Modeling Study of Drug Effects on Tumor Growth using Hybrid Systems
por: Li, Xiangfang, et al.
Publicado: (2012)

A Bayesian approach to determine the composition of heterogeneous cancer tissue
por: Katiyar, Ashish, et al.
Publicado: (2018)

Causality, Randomness, Intelligibility, and the Epistemology of the Cell
por: Dougherty, Edward R, et al.
Publicado: (2010)

Epistemology of the cell: a systems perspective on biological knowledge
por: Dougherty, Edward R, et al.
Publicado: (2011)

Newton, Laplace, and The Epistemology of Systems Biology
por: Bittner, Michael L., et al.
Publicado: (2012)

Characterizing circulating nucleosomes in the plasma of dogs with lymphoma
por: Dolan, Christopher, et al.
Publicado: (2021)

Characterizing circulating nucleosomes in the plasma of dogs with hemangiosarcoma
por: Wilson-Robles, Heather, et al.
Publicado: (2021)

Unbiased bootstrap error estimation for linear discriminant analysis
por: Vu, Thang, et al.
Publicado: (2014)

Quantification of the Impact of Feature Selection on the Variance of Cross-Validation Error Estimation
por: Xiao, Yufei, et al.
Publicado: (2007)

Decorrelation of the True and Estimated Classifier Errors in High-Dimensional Settings
por: Hanczar, Blaise, et al.
Publicado: (2007)

Inference of Gene Regulatory Networks Using Time-Series Data: A Survey
por: Sima, Chao, et al.
Publicado: (2009)

Noise-injected neural networks show promise for use on small-sample expression data
por: Hua, Jianping, et al.
Publicado: (2006)

Evaluation of nucleosome concentrations in healthy dogs and dogs with cancer
por: Wilson-Robles, Heather, et al.
Publicado: (2020)

Characterization of the Effectiveness of Reporting Lists of Small Feature Sets Relative to the Accuracy of the Prior Biological Knowledge
por: Zhao, Chen, et al.
Publicado: (2010)

Monitoring plasma nucleosome concentrations to measure disease response and progression in dogs with hematopoietic malignancies
por: Wilson-Robles, Heather, et al.
Publicado: (2023)

Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus
por: Broussou, Diane C., et al.
Publicado: (2019)

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer
por: Malyutina, Alina, et al.
Publicado: (2019)

Temporal dynamics of migration‐linked genetic variation are driven by streamflows and riverscape permeability
por: Kelson, Suzanne J., et al.
Publicado: (2020)

Identifying Genes Involved in Cyclic Processes by Combining Gene Expression Analysis and Prior Knowledge
por: Zhao, Wentao, et al.
Publicado: (2009)

Location Specificity of Transcranial Electrical Stimulation on Neuronal Electrodynamics: A Mathematical Model of Ion Channel Gating Dynamics and Ionic Flux Due to Neurostimulation
por: Lindberg, Kaia R., et al.
Publicado: (2019)

Drug efficacy on zoonotic nematodes of the Anisakidae family: new metabolic data
por: Polak, Iwona, et al.
Publicado: (2022)

The effect of multispectral image fusion enhancement on human efficiency
por: Bittner, Jennifer L., et al.
Publicado: (2017)

Dynamic enhancement of drug product labels to support drug safety, efficacy, and effectiveness
por: Boyce, Richard D, et al.
Publicado: (2013)

Dynamical Synergy of Drug Combinations during Cancer Chemotherapy
por: Castorina, Paolo, et al.
Publicado: (2022)

Drug-Initiated Synthesis of Polymer Prodrugs: Combining Simplicity and Efficacy in Drug Delivery†
por: Nicolas, Julien
Publicado: (2016)

Quantifying the effects of antiangiogenic and chemotherapy drug combinations on drug delivery and treatment efficacy
por: Yonucu, Sirin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9ihg5ajsubg5cpu1g14nlre6bp