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Pathway Implications of Aberrant Global Methylation in Adrenocortical Cancer
CONTEXT: Adrenocortical carcinomas (ACC) are a rare tumor type with a poor five-year survival rate and limited treatment options. OBJECTIVE: Understanding of the molecular pathogenesis of this disease has been aided by genomic analyses highlighting alterations in TP53, WNT, and IGF signaling pathway...
Autores principales: | Legendre, Christophe R., Demeure, Michael J., Whitsett, Timothy G., Gooden, Gerald C., Bussey, Kimberly J., Jung, Sungwon, Waibhav, Tembe, Kim, Seungchan, Salhia, Bodour |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786116/ https://www.ncbi.nlm.nih.gov/pubmed/26963385 http://dx.doi.org/10.1371/journal.pone.0150629 |
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