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Human PIEZO1 Ion Channel Functions as a Split Protein
PIEZO1 is a mechanosensitive eukaryotic cation-selective channel that rapidly inactivates in a voltage-dependent manner. We previously showed that a fluorescent protein could be encoded within the hPIEZO1 sequence without loss of function. In this work, we split the channel into two at this site and...
Autores principales: | Bae, Chilman, Suchyna, Thomas M., Ziegler, Lynn, Sachs, Frederick, Gottlieb, Philip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786117/ https://www.ncbi.nlm.nih.gov/pubmed/26963637 http://dx.doi.org/10.1371/journal.pone.0151289 |
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