Clusterin/Akt Up-Regulation Is Critical for GATA-4 Mediated Cytoprotection of Mesenchymal Stem Cells against Ischemia Injury

BACKGROUND: Clusterin (Clu) is a stress-responding protein with multiple biological functions. Our preliminary microarray studies show that clusterin was prominently upregulated in mesenchymal stem cells (MSCs) overexpressing GATA-4 (MSC(GATA-4)). We hypothesized that the upregulation of clusterin i...

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Detalles Bibliográficos
Autores principales: Yu, Bin, Yang, Yueting, Liu, Huan, Gong, Min, Millard, Ronald W., Wang, Yi-Gang, Ashraf, Muhammad, Xu, Meifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786134/
https://www.ncbi.nlm.nih.gov/pubmed/26962868
http://dx.doi.org/10.1371/journal.pone.0151542

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