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IL-10 Production Is Critical for Sustaining the Expansion of CD5(+) B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice
The development and progression of systemic lupus erythematosus is mediated by the complex interaction of genetic and environmental factors. To decipher the genetics that contribute to pathogenesis and the production of pathogenic autoantibodies, our lab has focused on the generation of congenic lup...
Autores principales: | Baglaenko, Yuriy, Manion, Kieran P., Chang, Nan-Hua, Gracey, Eric, Loh, Christina, Wither, Joan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786215/ https://www.ncbi.nlm.nih.gov/pubmed/26964093 http://dx.doi.org/10.1371/journal.pone.0150515 |
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