Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications

Multiple system atrophy (MSA) is a fatal rapidly progressive α-synucleinopathy, characterized by α-synuclein accumulation in oligodendrocytes. It is accepted that the pathological α-synuclein accumulation in the brain of MSA patients plays a leading role in the disease process, but little is known a...

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Detalles Bibliográficos
Autores principales: Schafferer, Simon, Khurana, Rimpi, Refolo, Violetta, Venezia, Serena, Sturm, Edith, Piatti, Paolo, Hechenberger, Clara, Hackl, Hubert, Kessler, Roman, Willi, Michaela, Gstir, Ronald, Krogsdam, Anne, Lusser, Alexandra, Poewe, Werner, Wenning, Gregor K., Hüttenhofer, Alexander, Stefanova, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786272/
https://www.ncbi.nlm.nih.gov/pubmed/26962858
http://dx.doi.org/10.1371/journal.pone.0150705

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