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Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice
Kainic acid (KA) is routinely used to elicit status epilepticus (SE) and epileptogenesis. Among the available KA administration protocols, intranasal instillation (IN) remains understudied. Dosages of KA were instilled IN in mice. Racine Scale and Video-EEG were used to assess and quantify SE onset....
Autores principales: | Sabilallah, Mounira, Fontanaud, Pierre, Linck, Nathalie, Boussadia, Badreddine, Peyroutou, Ronan, Lasgouzes, Thibault, Rassendren, François A., Marchi, Nicola, Hirbec, Helene E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786335/ https://www.ncbi.nlm.nih.gov/pubmed/26963100 http://dx.doi.org/10.1371/journal.pone.0150793 |
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