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Genomic epidemiology of artemisinin resistant malaria
The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which cause resistance in Southeast Asia are present at low freq...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786412/ https://www.ncbi.nlm.nih.gov/pubmed/26943619 http://dx.doi.org/10.7554/eLife.08714 |