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The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins

As a first-line vertebrate immune defense, the polymeric immunoglobulin receptor (pIgR) transports polymeric IgA and IgM across epithelia to mucosal secretions, where the cleaved ectodomain (secretory component; SC) becomes a component of secretory antibodies, or when unliganded, binds and excludes...

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Detalles Bibliográficos
Autores principales:	Stadtmueller, Beth M, Huey-Tubman, Kathryn E, López, Carlos J, Yang, Zhongyu, Hubbell, Wayne L, Bjorkman, Pamela J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786434/ https://www.ncbi.nlm.nih.gov/pubmed/26943617 http://dx.doi.org/10.7554/eLife.10640

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