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Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy
A challenge in the management of ‘white dot syndromes’ is the lack of sensitive objective measures of disease activity. Retinal thickness maps from spectral domain optical coherence tomography (SD-OCT) inform treatment decisions in other retinal conditions such as age-related macular degeneration an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786512/ https://www.ncbi.nlm.nih.gov/pubmed/26965893 http://dx.doi.org/10.1186/s12348-016-0073-4 |
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author | Madhusudhan, Savitha Keane, Pearse A. Denniston, Alastair K. |
author_facet | Madhusudhan, Savitha Keane, Pearse A. Denniston, Alastair K. |
author_sort | Madhusudhan, Savitha |
collection | PubMed |
description | A challenge in the management of ‘white dot syndromes’ is the lack of sensitive objective measures of disease activity. Retinal thickness maps from spectral domain optical coherence tomography (SD-OCT) inform treatment decisions in other retinal conditions such as age-related macular degeneration and diabetic maculopathy. In this report, we demonstrate their value in providing quantitative monitoring of a patient with punctate inner choroidopathy (PIC). Retinal thickness maps referenced against a baseline scan reliably detected focal areas of increased macular volume in active PIC lesions during symptomatic episodes, highlighting these as ‘hot spots’ that could be quantified, providing an objective basis for treatment decisions. |
format | Online Article Text |
id | pubmed-4786512 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-47865122016-04-09 Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy Madhusudhan, Savitha Keane, Pearse A. Denniston, Alastair K. J Ophthalmic Inflamm Infect Letter to the Editor A challenge in the management of ‘white dot syndromes’ is the lack of sensitive objective measures of disease activity. Retinal thickness maps from spectral domain optical coherence tomography (SD-OCT) inform treatment decisions in other retinal conditions such as age-related macular degeneration and diabetic maculopathy. In this report, we demonstrate their value in providing quantitative monitoring of a patient with punctate inner choroidopathy (PIC). Retinal thickness maps referenced against a baseline scan reliably detected focal areas of increased macular volume in active PIC lesions during symptomatic episodes, highlighting these as ‘hot spots’ that could be quantified, providing an objective basis for treatment decisions. Springer Berlin Heidelberg 2016-03-10 /pmc/articles/PMC4786512/ /pubmed/26965893 http://dx.doi.org/10.1186/s12348-016-0073-4 Text en © Madhusudhan et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Letter to the Editor Madhusudhan, Savitha Keane, Pearse A. Denniston, Alastair K. Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
title | Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
title_full | Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
title_fullStr | Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
title_full_unstemmed | Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
title_short | Adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
title_sort | adjunctive use of systematic retinal thickness map analysis to monitor disease activity in punctate inner choroidopathy |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786512/ https://www.ncbi.nlm.nih.gov/pubmed/26965893 http://dx.doi.org/10.1186/s12348-016-0073-4 |
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