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Biotechnological production of limonene in microorganisms
This mini review describes novel, biotechnology-based, ways of producing the monoterpene limonene. Limonene is applied in relatively highly priced products, such as fragrances, and also has applications with lower value but large production volume, such as biomaterials. Limonene is currently produce...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786606/ https://www.ncbi.nlm.nih.gov/pubmed/26915992 http://dx.doi.org/10.1007/s00253-016-7337-7 |
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author | Jongedijk, Esmer Cankar, Katarina Buchhaupt, Markus Schrader, Jens Bouwmeester, Harro Beekwilder, Jules |
author_facet | Jongedijk, Esmer Cankar, Katarina Buchhaupt, Markus Schrader, Jens Bouwmeester, Harro Beekwilder, Jules |
author_sort | Jongedijk, Esmer |
collection | PubMed |
description | This mini review describes novel, biotechnology-based, ways of producing the monoterpene limonene. Limonene is applied in relatively highly priced products, such as fragrances, and also has applications with lower value but large production volume, such as biomaterials. Limonene is currently produced as a side product from the citrus juice industry, but the availability and quality are fluctuating and may be insufficient for novel bulk applications. Therefore, complementary microbial production of limonene would be interesting. Since limonene can be derivatized to high-value compounds, microbial platforms also have a great potential beyond just producing limonene. In this review, we discuss the ins and outs of microbial limonene production in comparison with plant-based and chemical production. Achievements and specific challenges for microbial production of limonene are discussed, especially in the light of bulk applications such as biomaterials. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00253-016-7337-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4786606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-47866062016-04-09 Biotechnological production of limonene in microorganisms Jongedijk, Esmer Cankar, Katarina Buchhaupt, Markus Schrader, Jens Bouwmeester, Harro Beekwilder, Jules Appl Microbiol Biotechnol Mini-Review This mini review describes novel, biotechnology-based, ways of producing the monoterpene limonene. Limonene is applied in relatively highly priced products, such as fragrances, and also has applications with lower value but large production volume, such as biomaterials. Limonene is currently produced as a side product from the citrus juice industry, but the availability and quality are fluctuating and may be insufficient for novel bulk applications. Therefore, complementary microbial production of limonene would be interesting. Since limonene can be derivatized to high-value compounds, microbial platforms also have a great potential beyond just producing limonene. In this review, we discuss the ins and outs of microbial limonene production in comparison with plant-based and chemical production. Achievements and specific challenges for microbial production of limonene are discussed, especially in the light of bulk applications such as biomaterials. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00253-016-7337-7) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2016-02-26 2016 /pmc/articles/PMC4786606/ /pubmed/26915992 http://dx.doi.org/10.1007/s00253-016-7337-7 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Mini-Review Jongedijk, Esmer Cankar, Katarina Buchhaupt, Markus Schrader, Jens Bouwmeester, Harro Beekwilder, Jules Biotechnological production of limonene in microorganisms |
title | Biotechnological production of limonene in microorganisms |
title_full | Biotechnological production of limonene in microorganisms |
title_fullStr | Biotechnological production of limonene in microorganisms |
title_full_unstemmed | Biotechnological production of limonene in microorganisms |
title_short | Biotechnological production of limonene in microorganisms |
title_sort | biotechnological production of limonene in microorganisms |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786606/ https://www.ncbi.nlm.nih.gov/pubmed/26915992 http://dx.doi.org/10.1007/s00253-016-7337-7 |
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