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Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex

Mcm10 is required for the initiation of eukaryotic DNA replication and contributes in some unknown way to the activation of the Cdc45-MCM-GINS (CMG) helicase. How Mcm10 is localized to sites of replication initiation is unclear, as current models indicate that direct binding to minichromosome mainte...

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Detalles Bibliográficos
Autores principales:	Douglas, Max E., Diffley, John F. X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786722/ https://www.ncbi.nlm.nih.gov/pubmed/26719337 http://dx.doi.org/10.1074/jbc.M115.707802

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