Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases

Prenylation reactions play crucial roles in controlling the activities of biomolecules. Bacterial prenyltransferases, TleC from Streptomyces blastmyceticus and MpnD from Marinactinospora thermotolerans, catalyse the ‘reverse' prenylation of (−)-indolactam V at the C-7 position of the indole rin...

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Detalles Bibliográficos
Autores principales: Mori, Takahiro, Zhang, Lihan, Awakawa, Takayoshi, Hoshino, Shotaro, Okada, Masahiro, Morita, Hiroyuki, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786772/
https://www.ncbi.nlm.nih.gov/pubmed/26952246
http://dx.doi.org/10.1038/ncomms10849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786772/
https://www.ncbi.nlm.nih.gov/pubmed/26952246
http://dx.doi.org/10.1038/ncomms10849

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