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A ligand-independent integrin β1 mechanosensory complex guides spindle orientation

Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while defects are associated with tumorigenesis and other diseases. Force sensing is one of the mechanisms through which division orientation is determined. Here we show that inte...

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Detalles Bibliográficos
Autores principales: Petridou, Nicoletta I., Skourides, Paris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786777/
https://www.ncbi.nlm.nih.gov/pubmed/26952307
http://dx.doi.org/10.1038/ncomms10899