The Wnt/β-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cells

Hypoxia, a feature common to most solid tumors, is known to regulate many aspects of tumorigenesis. Recently, it was suggested that hypoxia increased the size of the cancer stem-cell (CSC) subpopulations and promoted the acquisition of a CSC-like phenotype. However, candidate hypoxia-regulated media...

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Detalles Bibliográficos
Autores principales: Dong, Hye-Jin, Jang, Gyu-Beom, Lee, Hwa-Yong, Park, Se-Ra, Kim, Ji-Young, Nam, Jeong-Seok, Hong, In-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786801/
https://www.ncbi.nlm.nih.gov/pubmed/26965643
http://dx.doi.org/10.1038/srep22966

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