Activation of c-Jun predicts a poor response to sorafenib in hepatocellular carcinoma: Preliminary Clinical Evidence

We determined the mitogen-activated protein kinase (MAPK) gene expression profile of acquired resistance in sorafenib-sensitive hepatocellular carcinoma (HCC) cells and aimed to identify c-Jun as an important molecule mediating the efficacy of sorafenib. Differences in gene expression of the MAPK si...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Xiao, Weikai, Zhang, Kunsong, Yin, Xiaoyu, Lai, Jiaming, Liang, Lijian, Chen, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786823/
https://www.ncbi.nlm.nih.gov/pubmed/26964667
http://dx.doi.org/10.1038/srep22976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786823/
https://www.ncbi.nlm.nih.gov/pubmed/26964667
http://dx.doi.org/10.1038/srep22976

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