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A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides

Cyclotides are plant cyclic cysteine-rich peptides (CRPs). The cyclic nature is reported to be gene-determined with a precursor containing a cyclization-competent domain which contains an essential C-terminal Asn/Asp (Asx) processing signal recognized by a cyclase. Linear forms of cyclotides are rar...

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Detalles Bibliográficos
Autores principales: Serra, Aida, Hemu, Xinya, Nguyen, Giang K. T., Nguyen, Ngan T. K., Sze, Siu Kwan, Tam, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786859/
https://www.ncbi.nlm.nih.gov/pubmed/26965458
http://dx.doi.org/10.1038/srep23005