The G(q) signalling pathway inhibits brown and beige adipose tissue

Brown adipose tissue (BAT) dissipates nutritional energy as heat via the uncoupling protein-1 (UCP1) and BAT activity correlates with leanness in human adults. Here we profile G protein-coupled receptors (GPCRs) in brown adipocytes to identify druggable regulators of BAT. Twenty-one per cent of the...

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Detalles Bibliográficos
Autores principales: Klepac, Katarina, Kilić, Ana, Gnad, Thorsten, Brown, Loren M., Herrmann, Beate, Wilderman, Andrea, Balkow, Aileen, Glöde, Anja, Simon, Katharina, Lidell, Martin E., Betz, Matthias J., Enerbäck, Sven, Wess, Jürgen, Freichel, Marc, Blüher, Matthias, König, Gabi, Kostenis, Evi, Insel, Paul A., Pfeifer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786868/
https://www.ncbi.nlm.nih.gov/pubmed/26955961
http://dx.doi.org/10.1038/ncomms10895

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