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Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system

Applications of the CRISPR-Cas9 system to edit the genome have widely expanded to include DNA gene knock-out, deletions, chromosomal rearrangements, RNA editing and genome-wide screenings. Here we show the application of CRISPR-Cas9 technology to edit the mouse and human immunoglobulin (Ig) genes. B...

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Detalles Bibliográficos
Autores principales:	Cheong, Taek-Chin, Compagno, Mara, Chiarle, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786874/ https://www.ncbi.nlm.nih.gov/pubmed/26956543 http://dx.doi.org/10.1038/ncomms10934

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