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The biological significance of brain barrier mechanisms: help or hindrance in drug delivery to the central nervous system?
Barrier mechanisms in the brain are important for its normal functioning and development. Stability of the brain’s internal environment, particularly with respect to its ionic composition, is a prerequisite for the fundamental basis of its function, namely transmission of nerve impulses. In addition...
Autores principales: | Saunders, Norman R., Habgood, Mark D., Møllgård, Kjeld, Dziegielewska, Katarzyna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786902/ https://www.ncbi.nlm.nih.gov/pubmed/26998242 http://dx.doi.org/10.12688/f1000research.7378.1 |
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